THE SPACE-BASED CAR-FOLLOWING MODEL: DEVELOPMENT AND APPLICATION FOR MANAGED MOTORWAY SYSTEM SAFETY EVALUATION

The Space-Based Car-Following Model: Development and Application for Managed Motorway System Safety Evaluation

Traffic safety studies need more than what the current micro-simulation models can provide, as they presume that all drivers exhibit safe behaviors.Therefore, existing micro-simulation models are inadequate to evaluate the safety impacts of managed motorway systems such as Variable Speed Limits.All microscopic Boron traffic simulation packages incl

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Dynamic Programming for Thermal Management of Automotive Fuel Cell Systems: Investigating Hydrogen Saving Potential

Thermal management strategies implemented on-board fuel cell electrified vehicles (FCEVs) are currently based on heuristic reactive approaches.In this framework, developing predictive thermal management approaches that anticipate the travel needs of FCEV users could lead to improved hydrogen savings.However, the theoretical hydrogen saving achievab

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Molecular Docking, ADMET Study, Synthesis, Characterization and Preliminary Antiproliferative Activity of Potential Histone Deacetylase Inhibitors with Isoxazole as New Zinc Binding Group

Histone acetylation is a highly interesting epigenetic target for drug therapy.Histone deacetylase enzymes (HDACs) are overexpressed in several diseases, including cancers.Most of the clinically used HDAC inhibitors involve hydroxamate group as a zinc-binding group (ZBG).Hydroxamates have a poor pharmacokinetic properties and high toxicity profile.

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